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KMID : 0378019870300100103
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New Medical Journal
1987 Volume.30 No. 10 p.103 ~ p.107
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Clinical Efficacy of Diethylamine Chromone Carboxylate (Fludarene^(®)) in Patients with Diabetic Nephropathy
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Abstract
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This study was performed´ for evaluation of therapeutic efficacy of diethylamine chromone carboxylate (Fludareneⓒ).in patients with diabetic nephropathy. In 20 patients of noninsulin dependent diabetes mellitus with moderate proteinuria. Fludarene was prescribed for 3 months. After 2 months of treatment, the amount of proteinuria was decreased to 52.4% and 39.2% at 3 months. In analyses of proteinura reduction degree, 25% of patients were partial remission and 15% were complete remission at 2 months of treatment. After 3 months of treatment, 25% of patients were partial remission and 55% were complete remission. During the course of treatment only a few side effect such as epigastric discomfort was noted. These observation suggested that Fludarene may be effective and safe drug in the treatment of diabetic
nephropathy.
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KEYWORD
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